Bio-nano interface

Interfacing biological and artificial systems at the nano-scale level is of interest for many applications of nanotechnology in biology and medicine. Two of our projects related to this general issue concern interfacing neuron networks to electronic circuits and the use of DNA derivatives as molecular wires.

Directed neuron growth

  • Neuron cells on patterned substrates
  • Signal transmission in tailored neuron networks


Bio-molecular wires

  • High resolution AFM of DNA molecules
  • Electrical conduction in DNA wires
  • Site-control of DNA molecules

Selected publications:

  • R. Segev, M. Benveniste, E. Hulata, N. Cohen, E. Kapon, Y. Shapira and E. Ben-Jacob,
    “Long Term Behavior of Lithographically Prepared In Vitro Neural Networks”
    Phys. Rev. Lett. 88, 118102-1/4 (2002).
  • A. Kotlyar, N. Borovok, T. Molotsky, D. Klinov, B. Dwir and E. Kapon,
    “Synthesis of novel poly(dG)-poly(dG)-poly(dC) Triplex Structure by Klenow exo(-) Fragment of DNA Polymerase I”
    Nucleic Acid Research 33, 6515-6521 (2005).